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1. Increase accuracy as fewer genomic regions are sequenced multiple times.

 

 

2. Readily adaptable to commercial kits; use far fewer toxic reagents than the Maxam-Gilbert method

 

 

Advantanges

Disadvantanges

 

 

 

 

1. It is time consuming for generating data

 

 

 

2. It is very costly

 

 

 

3. Whole genome cannot be sequenced at once because each reaction sequences  is around 500bp everytime

 

 

 

 

 

Prons & Cons 

Facaulty of Bioscience and Medical Engineering

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© 2014. by Tham Sin Ying & Woo Hui Ying

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